New discoveries in the pathogenesis and classification of vitiligo.
Identifieur interne : 000734 ( Main/Exploration ); précédent : 000733; suivant : 000735New discoveries in the pathogenesis and classification of vitiligo.
Auteurs : Michelle Rodrigues [Australie] ; Khaled Ezzedine [France] ; Iltefat Hamzavi [États-Unis] ; Amit G. Pandya [États-Unis] ; John E. Harris [États-Unis]Source :
- Journal of the American Academy of Dermatology [ 1097-6787 ] ; 2017.
Descripteurs français
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- MESH :
English descriptors
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- MESH :
Abstract
Vitiligo is a common autoimmune disease that progressively destroys melanocytes in the skin, resulting in the appearance of patchy depigmentation. This disfiguring condition frequently affects the face and other visible areas of the body, which can be psychologically devastating. The onset of vitiligo often occurs in younger individuals and progresses for life, resulting in a heavy burden of disease and decreased quality of life. Presentation patterns of vitiligo vary, and recognition of these patterns provides both diagnostic and prognostic clues. Recent insights into disease pathogenesis offer a better understanding of the natural history of the disease, its associations, and potential for future treatments. The first article in this continuing medical education series outlines typical and atypical presentations of vitiligo, how they reflect disease activity, prognosis, and response to treatment. Finally, we discuss disease associations, risk factors, and our current understanding of disease pathogenesis.
DOI: 10.1016/j.jaad.2016.10.048
PubMed: 28619550
Affiliations:
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Le document en format XML
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This disfiguring condition frequently affects the face and other visible areas of the body, which can be psychologically devastating. The onset of vitiligo often occurs in younger individuals and progresses for life, resulting in a heavy burden of disease and decreased quality of life. Presentation patterns of vitiligo vary, and recognition of these patterns provides both diagnostic and prognostic clues. Recent insights into disease pathogenesis offer a better understanding of the natural history of the disease, its associations, and potential for future treatments. The first article in this continuing medical education series outlines typical and atypical presentations of vitiligo, how they reflect disease activity, prognosis, and response to treatment. Finally, we discuss disease associations, risk factors, and our current understanding of disease pathogenesis.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>États-Unis</li></country><region><li>Massachusetts</li><li>Michigan</li><li>Texas</li><li>Île-de-France</li></region><settlement><li>Créteil</li></settlement></list><tree><country name="Australie"><noRegion><name sortKey="Rodrigues, Michelle" sort="Rodrigues, Michelle" uniqKey="Rodrigues M" first="Michelle" last="Rodrigues">Michelle Rodrigues</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Ezzedine, Khaled" sort="Ezzedine, Khaled" uniqKey="Ezzedine K" first="Khaled" last="Ezzedine">Khaled Ezzedine</name></region></country><country name="États-Unis"><region name="Michigan"><name sortKey="Hamzavi, Iltefat" sort="Hamzavi, Iltefat" uniqKey="Hamzavi I" first="Iltefat" last="Hamzavi">Iltefat Hamzavi</name></region><name sortKey="Harris, John E" sort="Harris, John E" uniqKey="Harris J" first="John E" last="Harris">John E. Harris</name><name sortKey="Pandya, Amit G" sort="Pandya, Amit G" uniqKey="Pandya A" first="Amit G" last="Pandya">Amit G. Pandya</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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